-Year Follow-Up After Primary Percutaneous oronary Intervention With a Paclitaxel-Eluting tent Versus a Bare-Metal Stent in Acute T-Segment Elevation Myocardial Infarction Follow-Up Study of the PASSION (Paclitaxel-Eluting Versus onventional Stent in Myocardial Infarction With ST-Segment Elevation) Trial
نویسندگان
چکیده
ackground In primary percutaneous coronary intervention for acute ST-segment elevation myocarial infarction (STEMI), the use of drug-eluting stents (DES) is still controversial. Several randomized ontrolled trials of DES, compared with bare-metal stents (BMS), with short-term follow-up showed a eduction in target lesion revascularization (TLR), but no differences in rates of cardiac death or reurrent myocardial infarction. Moreover, the occurrence of (very) late stent thrombosis (ST) contines to be of major concern, and, therefore, long-term follow-up results are needed.
منابع مشابه
Lack of long-term clinical benefit of thrombus aspiration during primary percutaneous coronary intervention with paclitaxel-eluting stents or bare-metal stents: post-hoc analysis of the PASSION-trial.
BACKGROUND Although current clinical guidelines recommend the use of thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI), previous studies evaluating TA demonstrated contradictory results. The aim of this study was to evaluate long-term clinical outcome after TA in adjunct to PPCI for acute ST-segment myocardial infarction (STEMI), as compared with conventional tre...
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BACKGROUND A catheter-based approach after fibrinolysis is recommended if fibrinolysis is likely to be successful in patients with acute ST-elevation myocardial infarction. We designed a 2x2 randomized, open-label, multicenter trial to evaluate the efficacy and safety of the paclitaxel-eluting stent and tirofiban administered after fibrinolysis but before catheterization to optimize the results...
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INTRODUCTION AND OBJECTIVES The use of second-generation drug-eluting stents compared with bare-metal stents in patients with ST-segment elevation myocardial infarction reduces the rate of major adverse cardiac events. We aimed to evaluate the impact of sex on the performance of everolimus-eluting stents vs bare-metal stents in ST-segment elevation myocardial infarction at 2-year follow-up. M...
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BACKGROUND Vascular responses to drug-eluting stents in ST-segment elevation myocardial infarction are unknown. In the prospective, multicenter Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial, patients with ST-segment elevation myocardial infarction within 12 hours of symptom onset were randomized 3:1 to TAXUS EXPRESS paclitaxel-eluting...
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